My silly little sequel to the 2000 TV movie "Grandma Got Run Over By A Reindeer" (which in turn was based on the 1979 song). Eve Spankenhemer (i.e. Grandma) once again finds herself caught in a supernatural encounter as she runs into a vampire while coming home from her charity duties. She is quickly attacked and drained of her blood., But the family never mourn for her as she comes home just fine with them unaware that she is now un-dead. Imbue with the powers of the night which make her feel much younger, Eve begins her nightly hunts for blood. Even her family isn't exempt from her hunger as her loyal grandson, Jake, finds out who too joins the the walking undead. It now falls to Daphne to find a way to stop her increasing vampric family members before she too finds herself with a hunger for blood.